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The Role of Tregs in Autoimmunity and Cancer Therapy
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can go rogue, leading to autoimmune diseases like type 1 diabetes, multiple sclerosis, or rheumatoid arthritis. On the other hand, understanding this mechanism has opened doors for organ transplants and cancer therapies. By manipulating Tregs, scientists can prevent rejection or even boost immune attack on tumors. This breakthrough was made possible by decades of research. Scientists like Shimon Sakaguchi identified regulatory T cells and their role in immune balance. Meanwhile, discoveries around the FOXP3 gene showed how Tregs are programmed to function. Together, these findings explained how the immune system distinguishes self from non-self, a question that puzzled immunologists for
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Surreal
art, surreal
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Ken
Ashley