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The Marvels of Metal-Organic Frameworks: Structure, Activation, and Real-World Applications
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their structure when exposed to moisture or real-world conditions. Not useful if they degrade in air or water. Activation: To use the pores, you have to remove guest molecules (like solvent) without collapsing the structure—“activating” the MOF while preserving porosity. Researchers developed strategies and materials that maintain permanent porosity. Synthesis scale and cost: Some MOFs are easy to make in tiny amounts in the lab, but scaling up, making them cost-efficient, reproducible, and safe is non-trivial. Researchers are working on synthesis routes, water-stable MOFs, hierarchical porosity (macro-, meso-, micropores), post-synthetic modifications. Recent Advances & Real-World Applications: The 2025 Nobel Prize
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Omar
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